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1

Alterations in Wnt- β -catenin and Pten signalling play distinct roles in endometrial cancer initiation and progression

van der Zee, Marten, Jia, Yundan, Wang, Yongyi, Heijmans-Antonissen, Claudia, Ewing, Patricia C, Franken, Patrick, DeMayo, Francesco J, Lydon, John P, Burger, Curt W, Fodde, Riccardo, Blok, Leen J

Journal:

The Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 4.93 MB

english, 2013

2

Isolation and androgen regulation of the human homeobox cDNA,NKX3.1

Prescott, James L., Blok, Leen, Tindall, Donald J.

Journal:

Year:

1998

Language:

english

File:

PDF, 342 KB

english, 1998

3

Identification of a gene on human chromosome 8q11 that is differentially expressed during prostate-cancer progression

Glenn T.G. Chang, Nita Tapsi, Martine Steenbeek, Leen J. Blok, Wytske M. van Weerden, Dirk C.J.G. van Alewijk, Bert H.J. Eussen, Gert J. van Steenbrugge, Albert O. Brinkmann

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 195 KB

english, 1999

4

Genome-wide pathway analysis of folate-responsive genes to unravel the pathogenesis of orofacial clefting in man

Bart J. B. Bliek, Régine P. M. Steegers-Theunissen, Leen J. Blok, Lindy A. M. Santegoets, Jan Lindemans, Ben A. Oostra, Eric A. P. Steegers, Annelies de Klein

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

2008

Language:

english

File:

PDF, 534 KB

english, 2008

5

EGF signalling in prostate cancer cell lines is inhibited by a high expression level of the endocytosis protein REPS2

Josien K. Oosterhoff, Liesbeth C. Kühne, J. Anton Grootegoed, Leen J. Blok

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 286 KB

english, 2005

6

Imiquimod-induced clearance of HPV is associated with normalization of immune cell counts in usual type vulvar intraepithelial neoplasia

Annelinde Terlou, Manon van Seters, Alex Kleinjan, Claudia Heijmans-Antonissen, Lindy A.M. Santegoets, Ilse Beckmann, Marc van Beurden, Theo J.M. Helmerhorst, Leen J. Blok

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 624 KB

english, 2010

7

Nonsteroidal anti-inflammatory drugs do not interfere with imiquimod treatment for usual type vulvar intraepithelial neoplasia

Annelinde Terlou, Alex Kleinjan, Ilse Beckmann, Claudia Heijmans-Antonissen, Manon van Seters, Lindy A.M. Santegoets, Marc van Beurden, Theo J.M. Helmerhorst, Leen J. Blok

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 550 KB

english, 2011

8

Isolation of cDNAs that are differentially expressed between androgen-dependent and androgen-independent prostate carcinoma cells using differential display PCR

Leen J. Blok, M. Vijay Kumar, Dr. Donald J. Tindall

Journal:

Year:

1995

Language:

english

File:

PDF, 1.82 MB

english, 1995

9

Microsomal epoxide hydrolase expression in the endometrial uterine corpus is regulated by progesterone during the menstrual cycle

Simone L. Popp, Ina S. Abele, Miriam B. Buck, Matthias B. Stope, Leen J. Blok, Payman Hanifi-Moghaddam, Curt W. Burger, Peter Fritz, Cornelius Knabbe

Journal:

Journal of Molecular Histology

Year:

2010

Language:

english

File:

PDF, 395 KB

english, 2010

10

Progesterone Receptor-B Induction of BIRC3 Protects Endometrial Cancer Cells from AP1-59-Mediated Apoptosis

Nikki L. Neubauer, Erin C. Ward, Parin Patel, Zhenxiao Lu, Irene Lee, Leen J. Blok, Payman Hanifi-Moghaddam, Julian Schink, J. Julie Kim

Journal:

Hormones and Cancer

Year:

2011

Language:

english

File:

PDF, 474 KB

english, 2011

11

REPS2/POB1 is downregulated during human prostate cancer progression and inhibits growth factor signalling in prostate cancer cells

Oosterhoff, Josien K, Penninkhof, Fred, Brinkmann, Albert O, Anton Grootegoed, J, Blok, Leen J

Journal:

Year:

2003

Language:

english

File:

PDF, 247 KB

english, 2003

12

Identification of REPS2 as a putative modulator of NF-κB activity in prostate cancer cells

Penninkhof, Fred, Grootegoed, J Anton, Blok, Leen J

Journal:

Year:

2004

Language:

english

File:

PDF, 240 KB

english, 2004

13

Premalignant epithelial disorders of the vulva: squamous vulvar intraepithelial neoplasia, vulvar Paget's disease and melanoma in situ

ANNELINDE TERLOU, LEEN J. BLOK, THEO J.M. HELMERHORST, MARC VAN BEURDEN

Journal:

Acta Obstetricia et Gynecologica Scandinavica

Year:

2010

Language:

english

File:

PDF, 139 KB

english, 2010

14

Interaction between sex hormones and WNT/β-catenin signal transduction in endometrial physiology and disease

Paul H. van der Horst, Yongyi Wang, Marten van der Zee, Curt W. Burger, Leen J. Blok

Journal:

Molecular and Cellular Endocrinology

Year:

2012

Language:

english

File:

PDF, 500 KB

english, 2012

15

Treatment of vulvar intraepithelial neoplasia with topical imiquimod: Seven years median follow-up of a randomized clinical trial

Annelinde Terlou, Manon van Seters, Patricia C. Ewing, Neil K. Aaronson, Chad M. Gundy, Claudia Heijmans-Antonissen, Wim G.V. Quint, Leen J. Blok, Marc van Beurden, Theo J.M. Helmerhorst

Journal:

Gynecologic Oncology

Year:

2011

Language:

english

File:

PDF, 711 KB

english, 2011

16

Histological and immunohistochemical evaluation of postmenopausal endometrium after 3 weeks of treatment with tibolone, estrogen only, or estrogen plus progestagen

Anet H.A. Klaassens, F. Heidy van Wijk, Payman Hanifi-Moghaddam, Bianca Sijmons, Patricia C. Ewing, Marian J. Ten Kate-Booij, G. Sjarlot Kooi, Helenius J. Kloosterboer, Leen J. Blok, Curt W. Burger

Journal:

Fertility and Sterility

Year:

2006

Language:

english

File:

PDF, 2.36 MB

english, 2006

17

Investigations into the molecular background of endometrial cancer

Leen J. Blok, Curt W. Burger

Journal:

International Congress Series

Year:

2005

Language:

english

File:

PDF, 70 KB

english, 2005

18

Signaling by estrogens and tamoxifen in the human endometrium

Susanne C.J.P. Gielen, Lindy A.M. Santegoets, Payman Hanifi-Moghaddam, Curt W. Burger, Leen J. Blok

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 246 KB

english, 2008

19

Loss of APC function in mesenchymal cells surrounding the Müllerian duct leads to myometrial defects in adult mice

Yongyi Wang, Yundan Jia, Patrick Franken, Ron Smits, Patricia C. Ewing, John P. Lydon, Francesco J. DeMayo, Curt W. Burger, J. Anton Grootegoed, Riccardo Fodde, Leen J. Blok

Journal:

Molecular and Cellular Endocrinology

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

20

Progesterone receptors in endometrial cancer invasion and metastasis: development of a mouse model

Eline E. Hanekamp, Susanne C.J.P. Gielen, Susanna A. van Oosterhoud, Curt W. Burger, J.Anton Grootegoed, Frans J. Huikeshoven, Leen J. Blok

Journal:

Year:

2003

Language:

english

File:

PDF, 307 KB

english, 2003

21

Characterization of a TPA-Response Element in the 5‘-Flanking Region of the Androgen Receptor Gene

M. VUAY KUMAR, EVAN A. JONES, SARA J. FELTS, MARCEIL D. BLEXRUD, MICHAEL E. GROSSMANN, LEEN J. BLOK, LUCY J. SCHMIDT, Dr. DONALD J. TINDALL

Journal:

Journal of Andrology

Year:

1998

Language:

english

File:

PDF, 1.30 MB

english, 1998

22

Immunization of carp (Cyprinus carpio) with a Vibrio anguillarum bacterin: Indications for a common mucosal immune system

Jan W.H.M. Rombout, Leen J. Blok, Cor H.J. Lamers, Egbert Egberts

Journal:

Developmental & Comparative Immunology

Year:

1986

Language:

english

File:

PDF, 945 KB

english, 1986

23

Identification of Quiescent, Stem-Like Cells in the Distal Female Reproductive Tract

Wang, Yongyi, Sacchetti, Andrea, van Dijk, Matthijs R., van der Zee, Marten, van der Horst, Paul H., Joosten, Rosalie, Burger, Curt W., Grootegoed, J. Anton, Blok, Leen J., Fodde, Riccardo, Cooney, Au

Journal:

Year:

2012

Language:

english

File:

PDF, 8.59 MB

english, 2012

24

Regulation of androgen receptor mRNA and protein in the rat testis by testosterone

Blok, Leen J., Bartlett, John M.S., Vries, Joan Bolt-de, Themmen, Axel P.N., Brinkmann, Albert O., Weinbauer, Gerhard F., Nieschlag, Eberhard, Anton Grootegoed, J.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1991

Language:

english

File:

PDF, 1.22 MB

english, 1991

25

Transcriptional regulation of androgen receptor gene expression in Sertoli cells and other cell types

Blok, Leen J., Themmen, Axel P.N., Peters, Antoine H.F.M., Trapman, Jan, Baarends, Willy M., Hoogerbrugge, Jos W., Grootegoed, J.Anton

Journal:

Molecular and Cellular Endocrinology

Year:

1992

Language:

english

File:

PDF, 1.20 MB

english, 1992

26

The rat androgen receptor gene promoter

Baarends, Willy M., Themmen, Axel P.N., Blok, Leen J., Mackenbach, Petra, Brinkmann, Albert O., Meijer, Dies, Faber, Peter W., Trapman, Jan, Grootegoed, J.Anton

Journal:

Molecular and Cellular Endocrinology

Year:

1990

Language:

english

File:

PDF, 1018 KB

english, 1990

27

Regulation of inhibin β B-subunit mRNA expression in rat Sertoli cells: consequences for the production of bioactive and immunoreactive inhibin

Klaij, Ingrid A., Timmerman, Marianna A., Blok, Leen J., Grootegoed, J.Anton, de Jong, Frank H.

Journal:

Molecular and Cellular Endocrinology

Year:

1992

Language:

english

File:

PDF, 945 KB

english, 1992

28

Follicle-stimulating hormone regulates androgen receptor mRNA in Sertoli cells

Blok, Leen J., Mackenbach, Petra, Trapman, Jan, Themmen, Axel P.N., Brinkmann, Albert O., Grootegoed, J.Anton

Journal:

Molecular and Cellular Endocrinology

Year:

1989

Language:

english

File:

PDF, 659 KB

english, 1989

29

Follitropin receptor down-regulation involves a cAMP-dependent post-transcriptional decrease of receptor mRNA expression

Themmen, Axel P.N., Blok, Leen J., Post, Miriam, Baarends, Willy M., Hoogerbrugge, Jos W., Parmentier, Marc, Vassart, Gilbert, Grootegoed, J.Anton

Journal:

Molecular and Cellular Endocrinology

Year:

1991

Language:

english

File:

PDF, 763 KB

english, 1991

30

The Mouse Androgen Receptor Gene Contains a Second Functional Promoter Which Is Regulated by Dihydrotestosterone

Grossmann, Michael E., Lindzey, Jonathan, Blok, Leen, Perry, Jaime E., Kumar, M. Vijay, Tindall, Donald J.

Journal:

Year:

1994

Language:

english

File:

PDF, 2.45 MB

english, 1994

31

Forskolin-Induced Dephosphorylation of the Androgen Receptor Impairs Ligand Binding

Blok, Leen J., de Ruiter, Petra E., Brinkmann, Albert O.

Journal:

Year:

1998

Language:

english

File:

PDF, 82 KB

english, 1998

32

Progesterone receptor membrane component 1 deficiency attenuates growth while promoting chemosensitivity of human endometrial xenograft tumors

Friel, Anne M., Zhang, Ling, Pru, Cindy A., Clark, Nicole C., McCallum, Melissa L., Blok, Leen J., Shioda, Toshi, Peluso, John J., Rueda, Bo R., Pru, James K.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

33

Cluster-analysis of androgen- and EGF-regulated genes in relation to the proliferation and invasion of prostate cancer cells

Oosterhoff, Josien Κ., Kühne, Liesbeth C., Grootegoed, J. Anton, Blok, Leen J.

Journal:

International Journal on Disability and Human Development

Year:

2005

Language:

english

File:

PDF, 1.66 MB

english, 2005

34

Ligand-Controlled Interaction of Histone Acetyltransferase Binding to ORC-1 (HBO1) with the N-Terminal Transactivating Domain of Progesterone Receptor Induces Steroid Receptor Coactivator 1-Dependent Coactivation of Transcription

Georgiakaki, Maria, Chabbert-Buffet, Nathalie, Dasen, Boris, Meduri, Geri, Wenk, Sandra, Rajhi, Leila, Amazit, Larbi, Chauchereau, Anne, Burger, Curt W., Blok, Leen J., Milgrom, Edwin, Lombès, Marc, G

Journal:

Molecular Endocrinology

Year:

2006

Language:

english

File:

PDF, 717 KB

english, 2006

35

Androgen Receptor Phosphorylation

Blok, Leen J, de Ruiter, Petra E, Brinkmann, Albert O

Journal:

Endocrine Research

Year:

1996

Language:

english

File:

PDF, 1.17 MB

english, 1996

36

Progesterone-induced miR-133a Inhibits the Proliferation of Endometrial Epithelial Cells

Pan, Jun-li, Yuan, Dong-zhi, Zhao, You-bo, Nie, Li, Lei, Yi, Liu, Min, Long, Yun, Zhang, Jin-hu, Blok, Leen J., Burger, Curt W., Yue, Li-min

Journal:

Acta Physiologica

Year:

2016

Language:

english

File:

PDF, 903 KB

english, 2016

37

Phosphorylation of androgen receptor isoforms

WONG, Hao Yun, BURGHOORN, Jan A., van LEEUWEN, Marije, de RUITER, Petra E., SCHIPPERS, Esther, BLOK, Leen J., LI, Ka Wan, DEKKER, Henk L., de JONG, Luitzen, TRAPMAN, Jan, GROOTEGOED, J. Anton, BRINKMA

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 461 KB

english, 2004

38

Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment†

Wetendorf, Margeaux, Wu, San-Pin, Wang, Xiaoqiu, Creighton, Chad J., Wang, Tianyuan, Lanz, Rainer B., Blok, Leen, Tsai, Sophia Y., Tsai, Ming-Jer, Lydon, John P., DeMayo, Francesco J.

Journal:

Biology of Reproduction

Year:

2017

Language:

english

File:

PDF, 13.30 MB

english, 2017

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